Institut Pasteur is a private, state-approved non-profit foundation for biomedical research, established in 1887 by Louis Pasteur and hosting some 2,782 people including approximately 600 tenured scientists, several hundred PhD students and post-doctoral fellows, dedicated engineers and technicians, as well as administrative staff.
As one of the most prestigious health research institutions in the world, 10 Institut Pasteur researchers have received a Nobel Prize. It has always worked closely with the industry and its Business Development and Technology Transfer Department operates as a gateway between inside research and outside product development.
The Institut Pasteur is also at the centre of a unique international network of 32 institutes, stretching across all five continents and all affiliated in partnerships.
The Hearing Institute
The IP members of Hearlight proposal all belong to the Hearing Institute (Institut de l’Audition), a new IP research centre gathering more than 60 research scientists of different expertise on auditory perception, physiology and mechanisms of auditory deficits. The Institute’s mission is to implement and promote fundamental and translational research to on auditory perception and related deficits. It has access to all IP facilities, but also has its own state of the art facilities for mouse behaviour, optical brain imaging, optogenetic, electrophysiology and histology.
The scientific environment at the Hearing Institute includes also specialists of human cochlear implant and genetics therapy in the cochlea. The expertise of these scientists in human auditory rehabilitation will help constructing the exploitation plan for cortical implant technologies during the Hearlight project as well as the unique expertise of IP for exploitation of biological results into biomedical applications.
Dr. Brice Bathellier
is CNRS Research Director, and director of the “Auditory system dynamics and multisensory processing team”, at the Hearing Institute, the new research center of Institut Pasteur. He is a specialist of mouse auditory system imaging, electrophysiology (in particular in auditory cortex), mouse auditory behaviors, and computational modeling.
Dr. Nicolas Michalski
is IP Research Scientist, and director of the “Plasticity and central auditory system team” at the Hearing Institute. He is a specialist of auditory physiology and cell biology (cochlea and cortex). He will provide mouse models of deafness for testing cortical implants in congenitally deaf mice (WP2.3).
Dr. Jérémie Barral
is CNRS Research Scientist, and director of the “Neural Coding in the Auditory System team”. He is a specialist of cochlea biophysics and optogenetics. His team will perform optogenetic stimulation of the mouse cochlea to compare neurometric performance of optogenetic cochlear and cortical implants (WP4.1).
Grants Office: reporting, amendments, consortium meetings
Electrophysiological calibration in cortex of mouse optogenetics cortical implants in WP1.2 & 1.3 and of optogenetic stimulation in cochlea (WP3.1)
Behavioural measurements for psychophysics in normal and optogenetically implanted mice WP2.1 & 2.3
Analysis of calibration data for the neurometric evaluation of implant strategies in WP3.1
Biocompatibility assays in WP4.1-3.
Project management in WP6
Organization of dissemination events in WP5
Contribution with expertise of the biomedical field to the exploitation and business plans in WP5.